Hypospadias and Genital DevelopmentLaurence S. Baskin Springer Science & Business Media, 2004 - 258 pages Section I. Human Studies.- Epidemiology of Hypospadias.- Endocrine Evaluation of Hypospadias.- Endocrine Abnormalities in Boys with Hypospadias.- Genetic and Clinical Studies on Hypospadias.- Section II. Mechanism of Genital Development.- Development of the Penile Urethra.- Anatomical Studies of the Mouse Genital Tubercle.- Anatomical Studies of the Fibroblast Growth Factor-10 Mutant, Sonic Hedge Hog Mutant, and Androgen Receptor Mutant Mouse Genital Tubercle.- Developmental Genetics of Hypospadias.- Development of the Mouse External Genitalia: Unique Model of Organogenesis.- New Concepts on the Development of the Vagina.- Section III. Endocrine Disruptors and Sexual Dimorphism in the Animal Kingdom.- Endocrine Disruption Overview: Are Males at Risk?.- Endocrine Disruption and Hypospadias.- Toxicant-Induced Hypospadias in the Male Rat.- Masculinization of Female Mammals: Lessons from Nature. |
Table des matières
II | 25 |
III | 31 |
IV | 45 |
V | 73 |
VI | 87 |
VII | 103 |
VIII | 123 |
X | 149 |
XI | 159 |
XII | 173 |
XIII | 189 |
XIV | 203 |
XV | 217 |
XVI | 243 |
| 255 | |
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Expressions et termes fréquents
abnormalities alpha-reductase analysis androgen receptor antiandrogens Baskin birth defects bladder boys with hypospadias cells chemicals clitoris cloacal membrane Cunha cytokeratin deficient mutant developmental disruptors distal ectodermal effects embryonic endocrine disruption endodermal environmental enzyme epithelium estrogen exposure expression external genitalia fetal FGF8 Figure formation function fungicide fusion gene genetic genital development genital tubercle gestation glans Gray Haraguchi hormone human hypospadias incidence of hypospadias increased inhibits isolated hypospadias Kelce Kurzrock linuron male rat malformations masculinization maternal mesenchymal mg/kg/day mice midline molecular morphogenesis mouse genital tubercle mutations newborn normal Ostby outgrowth patients Paulozzi Pediatrics penis phallus phenotype phthalate pregnancy prepuce prochloraz procymidone prostate proximal rates of hypospadias reductase risk severe hypospadias sexual differentiation Sonic hedgehog spotted hyena steroid syndrome testicular testosterone tissue Toxicol urethral development urethral epithelium urethral folds urethral groove urethral plate urethral seam urethral spongiosum urogenital sinus Urol Urology utero vagina ventral vinclozolin wild type