Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis"This book is an extraordinary integration of a lifetime of thought on the subject by an exceptional scholar. Morowitz logically, consistently, and persuasively moves to define arguments that will influence thought in a fundamental realm of biology." -Donald M. Engelman, Yale University "Morowitz develops a model of the origin of life in which cells originate first, proteins follow, and genes evolve last. This model contradicts conventional wisdom but has the distinct advantage of being testable; and is supported by evidence mustered from biology, biochemistry, and biophysics. Morowitz['s] expertise in all three disciplines is impressive."-Francisco J. Ayala, Dept. of Ecology and Evol. Biology, University of California, Irvine "In this short and clearly written book, Morowitz explores the origins of life. . . . His objective is elegantly achieved. . . . A stimulating analysis . . . [and] an excellent read." -A. E. Douglas, Times Higher Education Supplement "[A] book rich in provocative and stimulating ideas. . . . I recommend it to anyone who has ever thought seriously about the origin of life." -Vincent P. Cirillo, Quarterly Review of Biology |
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Table des matières
The Nature of the Problem | 1 |
The Study of Origins | 10 |
The TopDown Approach | 28 |
Generalizations from Contemporary Biology | 38 |
The Minimal Cell | 59 |
The BottomUp Approach | 69 |
Chemical Elements Hydrophobicity and | 85 |
The Logic of Replication | 98 |
Energy Complexity and Organization | 113 |
Underlying Chemical Mechanisms | 133 |
Networks | 150 |
Lessons from Contemporary Biochemistry | 160 |
The Scenario | 172 |
| 187 | |
Autres éditions - Tout afficher
Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis Harold J. Morowitz Aucun aperçu disponible - 1992 |
Expressions et termes fréquents
activity amino acids amphiphiles approach aqueous Archean atomic autotrophic bilayer biochemical biochemistry biogenesis biological systems biosphere bonds carbon catalysis catalysts cellular chemical networks chemical reactions chemistry chromophores complexity components compounds condensation consider contemporary cyanobacteria cycles Deamer discussed domain Earth electron elements energy flow entity environment enzymes equilibrium eukaryotes event evolutionary experimental flux formation fossil free energy function genetic genome high-energy hydrogen input intermediates laws lipid living cells living systems logic macromolecules material mechanisms membrane metabolic molecular molecules Morowitz mycoplasma nitrogen nonpolar nutrient organisms origin oxidized pathway phase phosphate phosphorus phosphorylation photosynthetic physics planet polyphosphates possible prebiotic prebiotic chemistry precursors present-day primitive principle of continuity processes prokaryotes properties protein protocell proton pyrophosphate radiation random redox replication result role self-replicating small molecules solar specific stromatolites structures sulfur surface synthesis temperature theory thermal thermodynamics tion transmembrane trophic level universal ancestor ur-organism vesicle
Références à ce livre
Informations bibliographiques
| Titre | Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis Bio-origins series |
| Auteur | Harold J. Morowitz |
| Éditeur | Yale University Press, 1993 |
| ISBN | 0300102100, 9780300102109 |
| Longueur | 208 pages |
| Exporter la citation | BiBTeX EndNote RefMan |