Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis"This book is an extraordinary integration of a lifetime of thought on the subject by an exceptional scholar. Morowitz logically, consistently, and persuasively moves to define arguments that will influence thought in a fundamental realm of biology." -Donald M. Engelman, Yale University "Morowitz develops a model of the origin of life in which cells originate first, proteins follow, and genes evolve last. This model contradicts conventional wisdom but has the distinct advantage of being testable; and is supported by evidence mustered from biology, biochemistry, and biophysics. Morowitz['s] expertise in all three disciplines is impressive."-Francisco J. Ayala, Dept. of Ecology and Evol. Biology, University of California, Irvine "In this short and clearly written book, Morowitz explores the origins of life. . . . His objective is elegantly achieved. . . . A stimulating analysis . . . [and] an excellent read." -A. E. Douglas, Times Higher Education Supplement "[A] book rich in provocative and stimulating ideas. . . . I recommend it to anyone who has ever thought seriously about the origin of life." -Vincent P. Cirillo, Quarterly Review of Biology |
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Table des matières
The Nature of the Problem | 1 |
The Study of Origins | 10 |
The TopDown Approach | 28 |
Generalizations from Contemporary Biology | 38 |
The Minimal Cell | 59 |
The BottomUp Approach | 69 |
Chemical Elements Hydrophobicity and | 85 |
The Logic of Replication | 98 |
Energy Complexity and Organization | 113 |
Underlying Chemical Mechanisms | 133 |
Networks | 150 |
Lessons from Contemporary Biochemistry | 160 |
The Scenario | 172 |
| 187 | |
Autres éditions - Tout afficher
Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis Harold J. Morowitz Aucun aperçu disponible - 1992 |
Expressions et termes fréquents
activity amino acids amphiphiles approach aqueous assume atomic begin biogenesis biological bonds cells cellular chapter chemical chemistry complexity components compounds concentrations consider consists constructs contain contemporary continuity cycles deals define detailed discussed domain early Earth electron elements energy entity environment equilibrium event example existence experimental flow formation fossil function genetic given growth intermediates involves laws leads living logic major material measure mechanisms membrane metabolic molecular molecules nature necessary Note occur organisms origin pathway period phase phosphate physics possible prebiotic present principle problem processes prokaryotes properties protein protocell radiation range reactions reason reduced represent result role separation specific stage statement step stromatolites structures suggested surface synthesis temperature theory thermodynamics tion transfer universal vesicle
Références à ce livre
Informations bibliographiques
| Titre | Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis Bio-origins series |
| Auteur | Harold J. Morowitz |
| Éditeur | Yale University Press, 1993 |
| ISBN | 0300102100, 9780300102109 |
| Longueur | 208 pages |
| Exporter la citation | BiBTeX EndNote RefMan |