Beginnings of Cellular Life: Metabolism Recapitulates Biogenesis
Yale University Press, 1993 - 208 pages
In this book an internationally renowned scientist presents a radically new theory of the origin of life on Earth 4 billion years ago.
Harold J. Morowitz postulates that the first step toward the origin of life was the spontaneous condensation of amphiphilic molecules to form vesicles (or protocells). This hypothesis provides a framework for reexamining the emergence of cellularity. Morowitz further proposes that core metabolic processes have not changed for some 3.8 billion years, so we can use a study of modern biochemistry to advance our knowledge about the chemical processes of the earliest protocells. Morowitz views origin of life issues from the perspective of certain constructs in the philosophy of science that provide guideposts to formulating and assessing hypotheses. This book presents a unique discussion among origin-of-life books on the relation between science and epistemology on the difficult problem of learning about the very distant past.
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The Nature of the Problem
The Study of Origins
The TopDown Approach
Generalizations from Contemporary Biology
The Minimal Cell
The BottomUp Approach
Chemical Elements Hydrophobicity and
The Logic of Replication
Autres éditions - Tout afficher
activity amino acids amphiphiles approach aqueous assume atomic begin biogenesis biological bonds cells cellular chapter chemical chemistry complexity components compounds concentrations consider consists constructs contain contemporary continuity cycles deals define detailed discussed domain early Earth electron elements energy entity environment equilibrium event example existence experimental flow formation fossil function genetic given growth intermediates involves laws leads living logic major material measure mechanisms membrane metabolic molecular molecules nature necessary Note occur organisms origin pathway period phase phosphate physics possible prebiotic present principle problem processes prokaryotes properties protein protocell radiation range reactions reason reduced represent result role separation specific stage statement step stromatolites structures suggested surface synthesis temperature theory thermodynamics tion transfer universal vesicle
Advances in Microbial Physiology, Volume 40
Aperçu limité - 1998
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