ague; and in 1638, the Countess of Cinchon, Regent of Peru, having derived great benefit from the new remedy, it was introduced into Europe. Although its alkaloid, quinine, is perhaps the nearest approach to a medical specific, and has diminished the death rate in certain regions to an amazing extent, its introduction was bitterly opposed by many conservative members of the medical profession, and in this opposition large numbers of ultra-Protestants joined, out of hostility to the Roman Church. In the heat of sectarian feeling the new remedy was stigmatized as "an invention of the devil"; and so strong was this opposition that it was not introduced into England until 1653, and even then its use was long held back, owing mainly to anti-Catholic feeling.

What the theological method on the ultra-Protestant side could do to help the world at this very time is seen in the fact that, while this struggle was going on, Hoffmann was attempting to give a scientific theory of the action of the devil in causing Job's boils. This effort at a quasiscientific explanation which should satisfy the theological spirit, comical as it at first seems, is really worthy of serious notice, because it must be considered as the beginning of that inevitable effort at compromise which we see in the history of every science when it begins to appear triumphant.*

But I pass to a typical conflict in our days, and in a Protestant country. In 1847, James Young Simpson, a Scotch physician, who afterward rose to the highest eminence in his profession, having advocated the use of anæsthetics in obstetrical cases, was immediately met by a storm of opposition. This hostility flowed from an ancient and time-honoured belief in Scotland. As far back as the year 1591, Eufame Macalyane, a lady of rank, being charged with

* For the opposition of the South American Church authorities to the introduction of coca, etc., see Martindale, Coca, Cocaine, and its Salts, London, 1886, p. 7. As to theological and sectarian resistance to quinine, see Russell, pp. 194, 253; also Eccles; also Meryon, History of Medicine, London, 1861, vol. i, p. 74, note. For the great decrease in deaths by fever after the use of Peruvian bark began, see statistical tables given in Russell, p. 252; and for Hoffmann's attempt at compromise, ibid., p. 294.

seeking the aid of Agnes Sampson for the relief of pain at the time of the birth of her two sons, was burned alive on the Castle Hill of Edinburgh; and this old theological view persisted even to the middle of the nineteenth century. From pulpit after pulpit Simpson's use of chloroform was denounced as impious and contrary to Holy Writ; texts were cited abundantly, the ordinary declaration being that to use chloroform was "to avoid one part of the primeval curse on woman." Simpson wrote pamphlet after pamphlet to defend the blessing which he brought into use; but he seemed about to be overcome, when he seized a new weapon, probably the most absurd by which a great cause was ever won: "My opponents forget," he said, "the twenty-first verse of the second chapter of Genesis; it is the record of the first surgical operation ever performed, and that text proves that the Maker of the universe, before he took the rib from Adam's side for the creation of Eve, caused a deep sleep to fall upon Adam." This was a stunning blow, but it did not entirely kill the opposition; they had strength left to maintain that the "deep sleep of Adam took place before the introduction of pain into the world-in a state of innocence." But now a new champion intervened—Thomas Chalmers with a few pungent arguments from his pulpit he scattered the enemy forever, and the greatest battle of science against suffering was won. This victory was won not less for religion. Wisely did those who raised the monument at Boston to one of the discoverers of anæsthetics inscribe upon its pedestal the words from our sacred text, "This also cometh forth from the Lord of hosts, which is wonderful in counsel, and excellent in working."

XI. FINAL BREAKING AWAY OF THE THEOLOGICAL THEORY IN MEDICINE.

While this development of history was going on, the central idea on which the whole theologic view rested-the idea

* For the case of Eufame Macalyane, see Dalyell, Darker Superstitions of Scotland, pp. 130, 133. For the contest of Simpson with Scotch ecclesiastical authorities, see Duns, Life of Sir J. Y. Simpson, London, 1873, pp. 215-222, and 256-260.

of diseases as resulting from the wrath of God or malice of Satan-was steadily weakened; and, out of the many things which show this, one may be selected as indicating the drift of thought among theologians themselves.

Toward the end of the eighteenth century the most eminent divines of the American branch of the Anglican Church framed their Book of Common Prayer. Abounding as it does in evidences of their wisdom and piety, few things are more noteworthy than a change made in the exhortation to the faithful to present themselves at the communion. While, in the old form laid down in the English Prayer Book, the minister was required to warn his flock not "to kindle God's wrath" or "provoke him to plague us with divers diseases and sundry kinds of death," from the American form all this and more of similar import in various services was left out.

Since that day progress in medical science has been rapid indeed, and at no period more so than during the last half of the nineteenth century.

The theological view of disease has steadily faded, and the theological hold upon medical education has been almost entirely relaxed. In three great fields, especially, discoveries have been made which have done much to disperse the atmosphere of miracle. First, there has come knowledge regarding the relation between imagination and medicine, which, though still defective, is of great importance. This relation has been noted during the whole history of the science. When the soldiers of the Prince of Orange, at the siege of Breda in 1625, were dying of scurvy by scores, he sent to the physicians "two or three small vials filled with a decoction of camomile, wormwood, and camphor, gave out that it was a very rare and precious medicine—a medicine of such virtue that two or three drops sufficed to impregnate a gallon of water, and that it had been obtained from the East with great difficulty and danger." This statement, made with much solemnity, deeply impressed the soldiers; they took the medicine eagerly, and great numbers recovered rapidly. Again, two centuries later, young Humphry Davy, being employed to apply the bulb of the thermometer to the tongues of certain patients at Bristol after they had inhaled various gases as remedies for disease, and finding

that the patients supposed this application of the thermometer-bulb was the cure, finally wrought cures by this application alone, without any use of the gases whatever. Innumerable cases of this sort have thrown a flood of light upon such cures as those wrought by Prince Hohenlohe, by the "metallic tractors," and by a multitude of other agencies temporarily in vogue, but, above all, upon the miraculous cures which in past ages have been so frequent and of which a few survive.

The second department is that of hypnotism. Within the last half-century many scattered indications have been collected and supplemented by thoughtful, patient investigators of genius, and especially by Braid in England and Charcot in France. Here, too, great inroads have been made upon the province hitherto sacred to miracle, and in 1888 the cathedral preacher, Steigenberger, of Augsburg, sounded an alarm. He declared his fears "lest accredited Church miracles lose their hold upon the public," denounced hypnotism as a doctrine of demons, and ended with the singular argument that, inasmuch as hypnotism is avowedly incapable of explaining all the wonders of history, it is idle to consider it at all. But investigations in hypnotism still go on, and may do much in the twentieth century to carry the world yet further from the realm of the miraculous.

In a third field science has won a striking series of victories. Bacteriology, beginning in the researches of Leeuwenhoek in the seventeenth century, continued by O. F. Müller in the eighteenth, and developed or applied with wonderful skill by Ehrenberg, Cohn, Lister, Pasteur, Koch, Billings, Bering, and their compeers in the nineteenth, has explained the origin and proposed the prevention or cure of various diseases widely prevailing, which until recently have been generally held to be "inscrutable providences." Finally, the closer study of psychology, especially in its relations to folklore, has revealed processes involved in the development of myths and legends: the phenomena of "expectant attention," the tendency to marvel-mongering, and the feeling of "joy in believing."

In summing up the history of this long struggle between science and theology, two main facts are to be noted: First,

that in proportion as the world approached the "ages of faith" it receded from ascertained truth, and in proportion as the world has receded from the "ages of faith" it has approached ascertained truth; secondly, that, in proportion as the grasp of theology upon education tightened, medicine declined, and in proportion as that grasp has relaxed, medicine has been developed.

The world is hardly beyond the beginning of medical discoveries, yet they have already taken from theology what was formerly its strongest province-sweeping away from this vast field of human effort that belief in miracles which for more than twenty centuries has been the main stumblingblock in the path of medicine; and in doing this they have cleared higher paths not only for science, but for religion.

*For the rescue of medical education from the control of theology, especially in France, see Rambaud, La Civilisation Contemporaine en France, pp. 682, 683. For miraculous cures wrought by imagination, see Tuke, Influence of Mind on Body, vol. ii. For the opposition to scientific study of hypnotism, see Hypnotismus und Wunder: ein Vortrag, mit Weiterungen, von Max Steigenberger, Domprediger, Augsburg, 1888, reviewed in Science, February 15, 1889, p. 127. For a recent statement regarding the development of studies in hypnotism, see Liégeois, De la Suggestion et du Somnambulisme dans leurs rapports avec la Jurisprudence, Paris, 1889, chap. ii. As to joy in believing and exaggerating marvels, see in the London Graphic for January 2, 1892, an account of Hindu jugglers by " Professor " Hofmann, himself an expert conjurer. He shows that the Hindu performances have been grossly and persistently exaggerated in the accounts of travellers; that they are easily seen through, and greatly inferior to the jugglers' tricks seen every day in European capitals. The eminent Prof. De Gubernatis, who also had witnessed the Hindu performances, assured the present writer that the current accounts of them were monstrously exaggerated. As to the miraculous in general, the famous Essay of Hume holds a most important place in the older literature of the subject; but, for perhaps the most remarkable of all discussions of it, see Conyers Middleton, D. D., A Free Inquiry into the Miraculous Powers which are supposed to have subsisted in the Christian Church, London, 1749. For probably the most judicially fair discussion, see Lecky, History of European Morals, vol. i, chap. iii; also his Rationalism in Europe, vol. i, chaps. i and ii; and for perhaps the boldest and most suggestive of recent statements, see Max Müller, Physical Religion, being the Gifford Lectures before the University of Glasgow for 1890, London, 1891, lecture xiv. See also, for very cogent statement, and arguments, Matthew Arnold's Literature and Dogma, especially chap. v, and, for a recent utterance of great clearness and force, Prof. Osler's Address before the Johns Hopkins University, given in Science for March 27, 1891.