NMR Primer: An HSQC-based Approach with Vector Animations

Couverture
IM Publications, 2008 - 129 pages
"This book has one aim: to explain the key two-dimensional protein NMR experiment, the 1H,15N-HSQC, along with variants and extensions, in a generally accessible manner. Vector diagrams of one-, two- and three-dimensional pulse sequences are provided, along with accompanying animated versions. The animations allow the evolution of net magnetisation during the course of the experiments to be visualised and directly compared with the corresponding spin operator terms. First, a brief introduction to spins, populations, the NMR experiment and relaxation is provided. Evolution due to J-coupling is next described and used to explain magnetisation transfer in the HSQC experiment and several variants. The extraction of structural, sequential and dynamic information is then illustrated via various extensions of the HSQC. Extensive footnotes and appendices introduce several more advanced concepts, such as sensitivity enhancement and the TROSY effect."--Publisher's description.
 

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Table des matières

summary
9
summary
28
3d HSQCbased double resonance experiments
41
2HNCO
60
Fourier transform sign discrimination artefact suppression
73
R2R1
86
Transverse RelaxationOptimised SpectroscopY
95
BlochSiegert effect and BlochSiegert compensating pulses BSCP
108
Creating the cover image
121
Droits d'auteur

Expressions et termes fréquents

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