Biology of AgingGarland Science, 2 juil. 2013 - 360 pages Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging |
Table des matières
Basic Concepts in the Biology of Aging | 1 |
Measuring Biological Aging | 27 |
Evolutionary Theories of Longevity and Aging | 55 |
Cellular Aging | 81 |
Genetics of Longevity | 117 |
Plant Senescence | 163 |
Human Longevity | 187 |
The Physiology of Human Aging | 207 |
AgeRelated Disease In Humans | 253 |
Modulating Human Aging and Longevity | 305 |
Appendix | 331 |
339 | |
361 | |
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Expressions et termes fréquents
age-related disease aging and longevity Alzheimer’s disease amino acids animals arteries biogerontologists biological aging Biology of Aging body bone brain Ca2+ calorie restriction cause cell cycle cellular Chapter chloroplast chromosome cohort concentration cytokinin cytosol damage death decline decrease Drosophila effect elegans energy environment environmental enzymes evolutionary extended longevity factors females Figure function gene expression genetic genome glucose growth heart hormone human aging increase individuals insulin intestine intracellular lipid loss males maximum life span mean life span mechanism membrane metabolism mice mitotic molecular molecules mortality rate mRNA muscle mutation neurons normal nutrients occurs organisms osteoblast osteoporosis oxidative oxygen Parkinson’s disease pathways phase phosphorylation photosynthesis physical activity physiological plant senescence population protein rate of aging receptor reduced regulation replicative senescence reproduction risk sequence signal species structure studies survival synthesis telomere tion tissue transcription type 2 diabetes yeast