The Dog and Its GenomeElaine A. Ostrander, Urs Giger, Lindblad-Toh Kerstin CSHL Press, 3 avr. 2007 - 584 pages Dogs of different breeds can range remarkably in size, shape, and behavior, and yet they all carry essentially the same genome, making them a particularly fascinating model for genome plasticity. The recent release of the complete sequence of the dog genome provides an exciting new context in which to consider such variation. Twentyfive chapters written by experts in the field include various aspects of morphological and behavioral variation in dogs, their origins and domestication, and their unique value as a model system for many common but complex human diseases such as diabetes and cancer. |
Table des matières
1 | |
19 | |
31 | |
47 | |
Morphological Loci in thePortuguese Water Dog Population | 67 |
Are TheyCoupled at the Genome Level? | 81 |
7 From Wild Wolf to Domestic Dog | 95 |
8 mtDNA Studies of the Originof Dogs | 119 |
Searchingfor Unique Phenotypes and Genesin the Dog Model of InheritedRetinal Degeneration | 291 |
17 Copper Toxicosis inBedlington Terriers | 327 |
18 Cystinuria | 349 |
19 Molecular Genetics of DilatedCardiomyopathy | 365 |
20 Sex Chromosomes SexualDevelopment and Sex Reversalin the Dog | 383 |
Strategies for CanineHip Dysplasia | 407 |
22 Breedspecific CanineLymphoproliferative Diseases | 439 |
23 Cancer Biology in Dogs | 451 |
The PhyDo Project | 141 |
10 Karyotype and ChromosomalOrganization | 159 |
Sequence Evolution and Haplotype Structure | 179 |
12 SINEs of Canine Genomic Diversity | 209 |
13 The Dog Olfactory and VomeronasalReceptor Repertoires | 221 |
14 The Canine MajorHistocompatibility Complex | 233 |
15 Breedspecific Hereditary Diseasesand Genetic Screening | 249 |
24 Gene Therapy for MetabolicInherited Diseases in Dogs | 473 |
Humanlike Social Skills in Dogs AreHeritable and Derived | 497 |
What CanDogs and Silver Foxes Tell Usabout Each Other? | 515 |
AKC Recognized Dog Breeds | 539 |
Index | 567 |
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Expressions et termes fréquents
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