Biology of Aging

Couverture
Garland Science, 7 juin 2019 - 456 pages

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material.

Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at rbmcdonald@ucdavis.edu.

Related Titles

Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1)

Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4)

Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

 

Table des matières

Basic Concepts in the Biology of Aging
1
Measuring Biological Aging
37
Evolutionary Theories of Longevity and Aging
67
Cellular Aging
93
Genetics of Longevity
133
Plant Senescence
185
Human Longevity and Life Span
209
Common Functional Loss Associated with Aging
233
Common timedependent disease in humans
289
Modulating Human Aging and Longevity
345
Implications of an Extended Healthspan
373
Us Life Table Calculations
389
Glossary
397
Index
421
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À propos de l'auteur (2019)

Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at rbmcdonald@ucdavis.edu.

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