Metals, Fertility, and Reproductive Toxicity

Couverture
Mari S. Golub
CRC Press, 10 nov. 2005 - 280 pages
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Environmental endocrine disruptors have been at the heart of discussions about chemicals and their effects on fertility, but the focus has been on organic compounds and the role of metals has been largely overlooked - until now. Taking an organ-system-based approach, Metals, Fertility, and Reproductive Toxicity examines the effects of metals found in the everyday environment on fertility rates in humans and animal populations.

This volume summarizes and evaluates the literature in the area of metal effects on fertility and reproduction in humans, laboratory animals, and wildlife. International experts have contributed chapters that explore how the ovary, testes, uterine system, and neuroendocrine system, among others, respond to metal exposure. Reviewing both current knowledge and cutting edge data, the chapters focus on either a particular metal or a particular population.

A massive amount of data on this subject has been generated, summarized, and reviewed over the years. While there are many books available on metals toxicity and on reproductive toxicity, no current book explores both in the same volume. Culling information from throughout the literature, Metals, Fertility, and Reproductive Toxicity supplies an in-depth look at the role of metals in endocrine disruption and the spectrum of mechanisms involving metals that can influence reproduction.
 

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Table des matières

Cadmium
9
Reproductive Toxicity of Mercury Cadmium and Arsenic
19
Adverse Effects of Aluminum Uranium and Vanadium
65
Intrauterine and Reproductive Toxicity of Nutritionally
93
Lead Exposure and Its Effects on the Reproductive
117
Impact of Metals on Ovarian Function
155
Epidemiological and Occupational Studies of Metals
175
Use of Metal Reproductive Toxicity Data in Selecting
213
Index
245
Droits d'auteur

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Expressions et termes fréquents

Fréquemment cités

Page 58 - Epstein, SS, Arnold, E., Andrea, J., Bass, W., and Bishop, Y.: Detection of chemical mutagens by the dominant lethal assay in the mouse.
Page 21 - Placental element levels in relation to fetal development for obstetrically "normal" births: a study of 37 elements. Evidence for effects of cadmium, lead and zinc on fetal growth, and for smoking as a source of cadmium.
Page 243 - Reiter, LW, Anderson, GE, Laskey, JW and Cahill, DF (1975). Developmental and Behavioral Changes in the Rat During Chronic Exposure to Lead.
Page 172 - Richards JS, Jahnsen T, Hedin L, Lifka J, Ratoosh S, Durica JM Goldring NB 1987.
Page 210 - Occupation of father at time of birth of children dying of malignant diseases.
Page 19 - The relationship between cadmium, zinc, and birth weight in pregnant women who smoke. Am J Obstet Gynecol 1987:157:1247-51.
Page 242 - Chronic low-level lead toxicity in the rat: II. Effects on postnatal physical and behavioral development. Toxicol. Appl. Pharmacol.

Informations bibliographiques