Textbook of Bone MetastasesClaude Jasmin Wiley, 11 mars 2005 - 568 pages The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials The justification for a textbook on the subject of bone metastases is the quite remarkable progress made recently in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the pathophysiology of bone metastases and therapeutics.. This book provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases. |
Table des matières
Prostate Cancer | 39 |
Total En Bloc Spondylectomy for Spinal | 215 |
Percutaneous Injection of Ethanol | 415 |
Droits d'auteur | |
4 autres sections non affichées
Autres éditions - Tout afficher
Textbook of Bone Metastases Claude Jasmin,Rodolfo Capanna,Lawrence Coia,Robert Coleman,Gerard Saillant Aucun aperçu disponible - 2005 |
Textbook of Bone Metastases Claude Jasmin,Rodolfo Capanna,Lawrence Coia,Robert Coleman,Gerard Saillant Aucun aperçu disponible - 2005 |
Expressions et termes fréquents
activity adjuvant advanced breast cancer assessment biopsy bisphosphonates bone formation Bone Joint Surg bone marrow bone metastases Bone Min Res bone pain bone resorption bone scan breast cancer cancer cells Cancer Res carcinoma cement chemotherapy Clin Oncol Clin Orthop clinical clodronate cortical diagnosis distal dose effects evaluation femoral femur Figure fixation growth factors hormone humerus hypercalcaemia imaging increased inhibit injection involvement lesions long bones lytic malignant markers of bone metastatic bone disease metastatic breast cancer metastatic disease multiple myeloma Oncology osteoclast osteolytic osteoprotegerin pain relief pamidronate parathyroid hormone-related protein pathological fractures patients with bone patients with metastatic placebo posterior postmenopausal prostate cancer protein proximal PTHrP radiation therapy radiographs radiotherapy randomised RANKL receptor reconstruction reduce resection response rate serum skeletal complications skeletal metastases soft tissue spine surgery surgical survival tamoxifen tion treated treatment trial tumour tumour cells vertebral body vertebroplasty zoledronic acid