Cystic Fibrosis: Renewed Hopes Through Research

Couverture
Dinesh Sriramulu
BoD – Books on Demand, 28 mars 2012 - 564 pages
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Living healthy is all one wants, but the genetics behind creation of every human is different. As a curse or human agony, some are born with congenital defects in their menu of the genome. Just one has to live with that! The complexity of cystic fibrosis condition, which is rather a slow-killer, affects various organ systems of the human body complicating further with secondary infections. That's what makes the disease so puzzling for which scientists around the world are trying to understand better and to find a cure. Though they narrowed down to a single target gene, the tentacles of the disease reach many unknown corners of the human body. Decades of scientific research in the field of chronic illnesses like this one surely increased the level of life expectancy. This book is the compilation of interesting chapters contributed by eminent interdisciplinary scientists around the world trying to make the life of cystic fibrosis patients better.
 

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Table des matières

The Prognosis of Cystic Fibrosis
3
Radiological Features of Cystic Fibrosis
31
Past Observations
51
Cystic Fibrosis and Infertility
67
Genotype Phenotype Relationship
91
Biochemical and Molecular Genetic Testing Used
123
Pseudomonas aeruginosa Biofilm Formation
153
Outcome and Prevention of Pseudomonas aeruginosa
181
Channel Replacement Therapy for Cystic Fibrosis
291
Fine Tuning of CFTR Traffic
359
CFTR Gene Transfer and Tracking
379
VIP as a Corrector
397
Pharmacological Potential
413
Pharmacological Modulators of Sphingolipid Metabolism
439
The Importance of Adherence
455
Improving the Likelihood of Success in Trials
473

Infection by Non Tuberculous
207
Diversity
225
Viral Respiratory Tract Infections in Cystic Fibrosis
253
Immune Dysfunction in Cystic Fibrosis
273
The Physiotherapists Use of Exercise
519
Exercise Performance
541
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