Organic ChemistryOUP Oxford, 15 mars 2012 - 1234 pages Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the students' choice of organic chemistry text. This second edition takes all that has made Organic Chemistry the book of choice, and has refined and refocused it to produce a text that is even more student-friendly, more coherent and more logical in its presentation than before. At heart, the second edition remains true to the first, being built on three principles: An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts; A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered; An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding. The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles. Enriched with an extensive bank of online resources to help the reader visualise the structure of organic compounds and their reaction mechanisms, this second edition reaffirms the position of Organic Chemistry as the essential course companion for all organic chemistry students. Online Resource Centre For students: A range of problems to accompany each chapter For registered adopters of the text: Figures from the book in electronic format |
Table des matières
| 1 | |
| 15 | |
| 43 | |
4 Structure of molecules | 80 |
5 Organic reactions | 107 |
6 Nucleophilic addition to the carbonyl group | 125 |
7 Delocalization and conjugation | 141 |
8 Acidity basicity and pKsuba | 163 |
25 Alkylation of enolates | 584 |
the aldol and Claisen reactions | 614 |
27 Sulfur silicon and phosphorus in organic chemistry | 656 |
28 Retrosynthetic analysis | 694 |
reactions | 723 |
synthesis | 757 |
31 Saturated heterocycles and stereoelectronics | 789 |
32 Stereoselectivity in cyclic molecules | 825 |
9 Using organometallic reagents to make CC bonds | 182 |
10 Nucleophilic substitution at the carbonyl group | 197 |
11 Nucleophilic substitution at CO with loss of carbonyl oxygen | 222 |
12 Equilibria rates and mechanisms | 240 |
Proton nuclear magnetic resonance | 269 |
14 Stereochemistry | 302 |
15 Nucleophilic substitution at saturated carbon | 328 |
16 Conformational analysis | 360 |
17 Elimination reactions | 382 |
18 Review of spectroscopic methods | 407 |
19 Electrophilic addition to alkenes | 427 |
20 Formation and reactions of enols and enolates | 449 |
21 Electrophilic aromatic substitution | 471 |
22 Conjugate addition and nucleophilic aromatic substitution | 498 |
23 Chemoselectivity and protecting groups | 528 |
24 Regioselectivity | 562 |
33 Diastereoselectivity | 852 |
cycloadditions | 877 |
sigmatropic and electrocyclic reactions | 909 |
36 Participation rearrangement and fragmentation | 931 |
37 Radical reactions | 970 |
38 Synthesis and reactions of carbenes | 1003 |
39 Determining reaction mechanisms | 1029 |
40 Organometallic chemistry | 1069 |
41 Asymmetric synthesis | 1102 |
42 Organic chemistry of life | 1134 |
43 Organic chemistry today | 1169 |
Figure acknowledgements | 1182 |
Periodic table of the elements | 1184 |
Index | 1187 |
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Expressions et termes fréquents
acetal acyl acyl chloride alcohol aldehyde aldol reaction alkene alkyl alkyne allylic amide amine amino anion aromatic axial base benzene bromine C–C bond carbon atom carbonyl compounds carbonyl group carboxylic acid cation Chapter chemistry chiral chloride Cl Cl CO2Et CO2H CO2Me conformation conjugate addition coupling cyclic cycloaddition delocalized deprotonation diastereoisomer Diels–Alder diene disconnection double bond electronegative electrons electrophilic elimination enamine enantiomers energy epoxide equatorial equilibrium ester example formation formed functional groups give H H H halides heterocycles hydrogen atoms hydrolysis imine Interactive mechanism intermediate isomer ketone leaving group lone pair LUMO methyl group molecular orbitals molecule nitro nitrogen atom NMR spectrum OH OH ortho oxidation oxygen atom Ph Ph proton pyridine react reactive reagents rearrangement retrosynthetic analysis rotation SN2 reaction solvent stable starting material step stereochemistry structure substitution sulfur synthesis tetrahedral trans yield