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which opium was very freely used, and which in a degree corroborate the opinion of Dr. Sutton, that opium must be used to the extent of producing sleep, and that sometimes it must be given in large quantity to produce that effect.

The first patient had taken an emetic and cathartic at the commencement of the disease, and afterwards opium in doses of two grains, repeated two or three times at intervals of an hour every day. Notwithstanding this he slept none during four days. At twelve o'clock in the night of the fourth day, after having taken in the evening six or eight grains of opium, he took two hundred drops of tincture of opium at once, and was allowed to walk some time bare headed in the open air. This calmed him a little. After this two doses of one hundred drops, and one of two hundred were given before four o'clock, and at this time four about grains of opium. In the course of two hours he began to sleep, and slept considerably during the day, at first short unquiet naps, which became longer and more quiet. By the sixth day from the attack he had become nearly rational.

The other patient at the commencement cut his throat, and lost from three to four pounds of blood. Tincture of opium in doses of fifty or sixty drops, repeated at longer or shorter intervals, was administered without good effect the two first days. At this time two hundred drops were given at a dose,



and one hundred repeated every half hour, till he had taken five hundred. He then began to dose, and from that time became more rational.

Both these patients rubbed their faces and breasts, as though they itched badly, after they had taken a large quantity of opium, and before any other evidence of its effect was discovered.






President of the Massachuselts Medical Society, A. A. S. &-c. &c.

Corresponding Secretary of the Society.

Read at the Annual Meeting, June 1, 1825, at the request of the Counsellors,

Nec unquam in suam famam gestis exsultavit

ita virtute in obsequendo, verecundiâ in prædicando, extra invidiam, nec extra gloriam erat.




conformity with the usages of our society, I had selected a medical topic for discussion, on the present occasion; but the decease of our President, involved the community in the most deep and poignant grief, and excited the sympathetic attention of your counsellors: They paid the tribute of their respect to his memory, and requested me to delineate his life and character, on this anniversary.* To do

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this, in a manner somewhat approaching to the dignity of the subject, and as would comport with your esteem and affection for him, it was necessary that I should relinquish my original design. Instead of

. directing your attention to the means of arresting the fatal grasp of the king of terrors, it has become my melancholy duty to lead you to contemplate the magnitude of his conquests.

Death is not awed by greatness, nor “warded off by virtues :" He seems to take delight in aiming his shafts at superior goodness, and in sending "those, who bear the brightest image of their maker, to mingle with kindred spirits.” But herein, he executes the benevolent designs of the Almighty; and the survivers are left the consoling and even delightful employment of displaying the excellencies of their departed friends, of portraying the beauties of their characters, and transmitting their bright examples to posterity.

If we look into the history of this Commonwealth, we find that many members of our profession have. signalized themselves for their talents as civilians, and for their ardor in maintaining the rights of the people; and some of them have been distinguished for their splendid achievements in war. Although these patriotic labors and exploits are foreign from the sciential pursuits of our profession, and from the objects for which this society was founded; yet we cannot be insensible spectators of events which involve the happiness of the community, nor of the glory which our country has derived from the im

perishable renown that these eminent patriots have acquired.

In a new country, individuals cannot devote themselves exclusively to science. The public exigencies call for the exertions of all classes of the people. In times of trouble and political coutests, men of education in every profession, are looked up to for council and advice, and they give a tone and direction to public opinion. It is well known to you, that the venerable clergy of New England, were among the most able and indefatigable assertors of our political rights: The sacred character of their duties, forbad them to engage in the labors of the senate, or to signalize themselves in the field; but they brought the aid of religion to our support. They appealed to the God of justice for the rectitude of our cause, and lighted up a holy flame of enthusiastic devotion to liberty, which burnt with a pure and steady brightness, until our glorious independence was accomplished.

These patriotic services were no less important to the cause of pure religion, than to the political state of the country. Religious liberty, or the public exercise of that liberty, has its foundation in the freedom of civil government. On the contrary, there is no tyranny so insufferable as that which is exercised over the mind, controlling its powers and its prerogatives in the great duties of devotion. Hence, our ancestors, the pilgrims, forsook the enjoyments of a polished society and a refined life, together with all the endearments of friends and kindred, and en

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