The Node of Ranvier

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Front Cover; The Node of Ranvier; Copyright Page; Table of Contents; Contributors; Preface; CHAPTER 1. EVOLUTIONAL ASPECTS OF THE STRUCTURE AND FUNCTION OF THE NODES OF RANVIER; I. Introduction; II. Morphology; III. Functional Parameters; IV. Electrophysiological Considerations; V. Conclusions; References; CHAPTER 2. MEMBRANE SPECIALIZATION AT THE NODES OF RANVIER AND PARANODAL AND JUXTAPARANODAL REGIONS OF MYELINATED CENTRAL AND PERIPHERAL NERVE FIBERS; I. Introduction; II. The Node of Ran vier; III. The Paranodal Region; IV. The Juxtaparanodal Internode; V. Developmental Studies. VI. Possible Mechanisms of Nodal DifferentiationVII. Effects of Demyelinating Agents; VIII. Aberrant Nodal and Paranodal Structures; References; CHAPTER 3. CATION BINDING AT THE NODE OF RANVIER; I. Introduction; II. Localization of Cation-Binding Reaction Product in the Normal, Myelinated Axon .; III. Localization of Binding during Development; IV. Cation Binding under Pathological Conditions; V. Cation Binding in Saltatory Conduction; VI. Conclusions; References; CHAPTER 4. FORMATION AND MORPHOLOGY OF THE NODES OF RANVIER IN CULTURES OF CNS AND PNS; I. Introduction; II. Nodes of Ranvier. III. Neurotoxic EffectsIV. Conclusion; References; CHAPTER 5. STRUCTURAL AND FUNCTIONAL RELATIONSHIPS OF ION CONDUCTION IN THE MYELINATED AND DEMYELINATED AXON; I. Introduction; II. Historical Development of the Description of Saltatory Conduction; III. Modern Study of the Molecular Architecture of Myelinated Nerve Membrane; IV. Pathophysiology of Conduction in Demyelinated Nerve Fibers; V. Conclusions; References; CHAPTER 6. STRUCTURE AND FUNCTION OF THE CYTOSKELETON AND ENDOMEMBRANE SYSTEMS AT THE NODE OF RANVIER; I. Introduction; II. General Organization of Eucaryotic Cytoplasm. III. Components of the Axonal Cytoskeleton and CytomusculatureIV. Endomembrane and Cisternal Systems of the Node and Paranode; V. Connections between the Cytoskeleton and the Endomembrane Systems; VI. Paranodal and Nodal Membrane Specializations as Shown by Freeze-Fracture; VII. Conclusions; References; CHAPTER 7. FUNCTIONAL ORGANIZATION OF POTASSIUM CHANNELS IN NORMAL AND PATHOLOGICAL MAMMALIAN AXONS; I. Introduction; II. Firing Characteristics and Accommodation of Normal and Pathological Axons ... III. Potassium Channels and Stabilization of Nodal Firing Properties during Axon MaturationIV. Role of Potassium Conductance in Activity-Dependent Excitability Changes; V. Electrical Field Effect Interactions in Normal and Pathological Nerve Bundles ... ; VI. Potassium Channel Organization in Pathological Axons; VII. Localization of Potassium Channels during Development and Regeneration; VIII. Concluding Remarks; References; CHAPTER 8. NODES OF RANVIER IN PATHOLOGICAL CONDITIONS; I. Introduction; II. The Normal Nodes; III. Pathology of the Node; References